LANA-DNA-IN-1 |
| カタログ番号GC71151 |
LANA-DNA-IN-1 は強力なLANA-DNA阻害剤である。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2512847-06-0
Sample solution is provided at 25 µL, 10mM.
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LANA-DNA-IN-1 has inhibition activity for LBS2, LBS1 and LBS3 with IC50 values of 8 μM, 9μM and 8μM in FP Assay[1].
LANA-DNA-IN-1 has potent LANA-LBS1-inhibitory with an IC50 values of 53 μM[1].
LANA-DNA-IN-1 (31.25, 62.5, 125 and 250 μM) has potent against wild-type LANA CTD and the oligomerization-deficient LANA DBD mutant[1].
References:
[1]. Philine Kirsch, et al. Hit-to-lead optimization of a latency-associated nuclear antigen inhibitor against Kaposi's sarcoma-associated herpesvirus infections. Eur J Med Chem. 2020 Sep 15;202:112525
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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