LDN 212854 trihydrochloride |
カタログ番号GB40259 |
強力なALK2バイアスBMPタイプI受容体キナーゼ阻害剤(ALK1、2、および3に対するIC50値はそれぞれ2.4 nM、1.3 nM、および85.8 nMであり、TGF-βとActivinタイプI受容体に密接に関連するものと比較してBMPに対する選択性が約4桁高い)。フリーベース形式のLDN 212854はLDN 212854として入手可能です。 LDN 193189に密接に関連しています。
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Cas No.: 2109414-80-2
Sample solution is provided at 25 µL, 10mM.
Potent ALK2-biased BMP type I receptor kinase inhibitor (IC50 values 2.4 nM, 1.3 nM, and 85.8 nM for ALK1, 2, and 3 resp.), showing nearly 4 orders of selectivity for BMP versus the closely related TGF-β and Activin type I receptors. The free base form, LDN 212854 is available as LDN 212854. Closely related to LDN 193189 .
Average Rating: 5
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