Limaprost-d3 (Synonyms: 17α,20-dimethyl-Δ2-PGE1-d3, 17α,20-dimethyl-Δ2-Prostaglandin E1-d3) |
| カタログ番号GC40239 |
Limaprost-d3は、GC-またはLC-MSによるリマプロストの定量のための内部標準として使用することを目的としています。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1263190-37-9
Sample solution is provided at 25 µL, 10mM.
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Limaprost-d3 is intended for use as an internal standard for the quantification of limaprost by GC- or LC-MS. Limaprost is an analog of prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is orally active in both rats and guinea pigs at doses of 100 µg/kg as an inhibitor of ADP and collagen-induced platelet aggregation. Limaprost is 10-1,000 times more potent than PGE1 as an inhibitor of platelet adhesiveness measured in vitro. Intra-coronary injection (100 ng/kg) or intravenous injection (3 µg/kg) in anesthetized dogs causes vasodilation and increased coronary blood flow by 60-80%. Significant hypotensive effects were seen at 100 and 300 µg/kg orally in rats.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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