LPA5 antagonist 1 |
カタログ番号GC71153 |
LPA5 antagonist 1(化合物66)は、強力で選択的なリシン酸レセプター5(LPA 5)アンタゴニスト(IC 50=32 nM)である。
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Cas No.: 2839471-45-1
Sample solution is provided at 25 µL, 10mM.
LPA5 antagonist 2 (0-10 μM) inhibits hLPA5 calcium mobilization with an IC50 value of 32 nM[1].
LPA5 antagonist 2 (0-10 μM) shows good target selectivity for LPA5[1].
LPA5 antagonist 1 (intraperitoneal injection; 17.8 mg/kg; once) treatment shows good brain exposure in vivo[1].
LPA5 antagonist 1 (intraperitoneal injection; 5.6, 10, and 17.8 mg/kg; once) treatment reduces mechanical allodynia in inflammatory pain model[1].
Average Rating: 5
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