Lumichrome (Synonyms: 7,8-Dimethylalloxazine, NSC 96911) |
| カタログ番号GC44090 |
リボフラビンの光分解産物であるルミクロムは、ヒトの内因性化合物です。ルミクロームは、ヒト肺がん細胞の増殖を阻害し、p53 依存メカニズムを介してアポトーシスを誘導します。
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Cas No.: 1086-80-2
Sample solution is provided at 25 µL, 10mM.
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Lumichrome is a natural metabolite of riboflavin. It can be made by photolysis of riboflavin or it can be produced enzymatically in certain microbes and plants. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at nanomolar concentrations. Lumichrome can stimulate larval metamorphosis in ascidians and activate the LasR quorum sensing receptor of bacteria. Lumichrome competitively inhibits the uptake of riboflavin by riboflavin transporters from prokaryotes and eukaryotes.
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