Luvadaxistat (Synonyms: TAK-831) |
| カタログ番号GC64018 |
TAK-831 は、D-アミノ酸オキシダーゼ (DAAO) の高度に選択的かつ強力な阻害剤であり、統合失調症の研究に使用できます 。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1425511-32-5
Sample solution is provided at 25 µL, 10mM.
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TAK-831 is a highly selective and potent inhibitor of D-amino acid oxidase (DAAO) and can be used in studies of schizophrenia[1][2].
[1]. Wang H, Norton J, Xu L, DeMartinis N, Sen R, Shah A, Farmer J, Lynch D. Results of a randomized double-blind study evaluating luvadaxistat in adults with Friedreich ataxia. Ann Clin Transl Neurol. 2021 Jun;8(6):1343-1352.
[2]. Yoneyama T, Sato S, Sykes A, Fradley R, Stafford S, Bechar S, Howley E, Patel T, Tagawa Y, Moriwaki T, Asahi S. Mechanistic Multilayer Quantitative Model for Nonlinear Pharmacokinetics, Target Occupancy and Pharmacodynamics (PK/TO/PD) Relationship of D-Amino Acid Oxidase Inhibitor, TAK-831 in Mice. Pharm Res. 2020 Aug 5;37(8):164.
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
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