LysoSensor PDMPO |
カタログ番号GC26349 |
PDMPO is an acidophilic lysosomal fluorescent probe and intracellular pH indicator that can be used for fluorescence imaging
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
LysoSensor Yellow/Blue DND-160 (LysoSensor PDMPO, PDMPO) is an acidophilic probe that accumulates in acidic lysosomes after protonation and is commonly used as a ratiometric marker of lysosomal pH (pK a is approximately 4.2). In addition to labeling acidic organelles, PDMPO has the added advantage of tracking pH fluctuations. PDMPO has pH-dependent dual excitation and dual emission spectrum peaks, producing blue fluorescence (Ex/Em=329nm/440nm) in a neutral environment and yellow fluorescence (Ex/Em=384nm/540nm). In addition, PDMPO has high fluorescence stability, which is beneficial for image-based assays [1].
References:
[1].L V Albrecht, N Tejeda-Muñoz, E M De Robertis. Protocol for Probing Regulated Lysosomal Activity and Function in Living Cells. 2020 Oct 17;1(3):100132. doi: 10.1016/j.xpro.2020.100132. eCollection 2020 Dec 18.
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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