m-PEG4-Tos |
| カタログ番号GC67208 |
m-PEG4-Tos は、特許 CN105037337A (化合物 III-b) から抽出されたシリビン エーテルの誘導体です。 m-PEG4-Tos は、シリマリンの合成に使用できる PEG ベースの PROTAC リンカーです。
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Cas No.: 62921-76-0
Sample solution is provided at 25 µL, 10mM.
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m-PEG4-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-b). m-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin [1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Yuxia Zhao, et al. Derivative of silybin ethers, and synthetic method and application thereof. Patent CN105037337A.
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