m-PEG9-NHS ester |
| カタログ番号GC67163 |
m-PEG9-NHS エステルは、PROTAC の合成に使用できる PEG ベースの PROTAC リンカーです。
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Cas No.: 1316189-13-5
Sample solution is provided at 25 µL, 10mM.
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m-PEG9-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Alexander Chucholowski, et al. Cyclodextrin conjugates. WO2010017328A2.
[2]. Satwik Kamtekar, et al. Modified biotin-binding proteins for immobilization. WO2019126734A1.
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