Maculosin (Synonyms: Cyclo(L-Pro-L-Tyr)) |
| カタログ番号GC18331 |
Maculosin は、Alternaria alternata の斑点のあるヤグルマギクに対する宿主特異的な植物毒素です。マクロシンは、緑膿菌による細胞間コミュニケーションに関与するクオラムセンシング分子です。マクロシンは、ラクトバチルス・ロイテリの病原性遺伝子発現を調節するシグナル伝達分子としても機能します。マクロシンは、抗酸化、抗癌、および非毒性の特性を示します。マクロシンは、48.90 μg/mL の IC50 で、ヒト肝癌細胞株に対して細胞傷害活性を示します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 74345-23-6,4549-02-4
Sample solution is provided at 25 µL, 10mM.
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Maculosin is a diketopiperazine metabolite produced by A. alternata, L. capsici, Streptomyces, and the Gram-negative, nonobligate predator bacterial strain 679-2. It acts as a host-specific phytotoxin, inducing formation of weeping necrotic lesions in leaves of spotted knapweed (C. maculosa) when used at a concentration of 10 μM. Maculosin reduces the growth of the plant pathogenic bacteria X. axonopodis and R. solanacearum (MICs = 31.25 μg/ml) as well as the pathogenic oomycetes P. cactorum, P. capsici, P. cinnamomi, P. infestans, and P. ultimum when used at concentrations ranging from 10 to 100 mg/ml. Maculosin also inhibits the growth of M. luteus, M. smegmatis, S. cerevisiae, C. albicans, C. neoformans, and A. niger when used in combination with pyrrolnitrin or banegasin.
Review for Maculosin
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
Review for Maculosin
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