Mitapivat (Synonyms: AG-348) |
カタログ番号GC19297 |
Mitapivat (AG-348) は、経口で活性なピルビン酸キナーゼ アロステリック活性化剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1260075-17-9
Sample solution is provided at 25 µL, 10mM.
Mitapivat is a potent human R-type pyruvate kinase (PKR) inhibitor; also shows potency for mutant PKR including R510Q PKR, R532W PKR, T384W PKR etc.
References:
[1]. PYRUVATE KINASE ACTIVATORS FOR USE IN THERAPY. Patent WO/2012/151451A1
Review for Mitapivat
Average Rating: 5
(Based on Reviews and 18 reference(s) in Google Scholar.)Review for Mitapivat
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