ML251 |
カタログ番号GC63076 |
ML251、強力なナノモル T.
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Cas No.: 1486482-16-9
Sample solution is provided at 25 µL, 10mM.
ML251, a potent nanomolar T. brucei and T. cruzi phosphofructokinase (PFK) inhibitor, inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1].
ML251 (T. brucei; 0~33.3 μg/mL) produces modest dose-dependent toxicity[1].
[1]. Brimacombe KR, et al. Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase. ACS Med Chem Lett. 2013;5(1):12-17.
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