MS7972 |
| カタログ番号GC62322 |
MS7972 は、ヒト p53 と CREB 結合タンパク質の会合をブロックする低分子です。 MS7972 は、50 μM でこの BRD 相互作用をほぼ完全にブロックできます。
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Cas No.: 352553-42-5
Sample solution is provided at 25 µL, 10mM.
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MS7972 is a small molecule that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM[1].
Addition of MS7972 to the CBP BRD results in emission at 445 nm and quenching of the CBP BRD due to resonance energy transfer[1].
[1]. Sachchidanand, et al. Target structure-based discovery of small molecules that block human p53 and CREB binding protein association. Chem Biol. 2006 Jan;13(1):81-90.
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