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N-3-hydroxybutyryl-L-Homoserine lactone (Synonyms: 3-OH-C4-HSL, N-3-hydroxybutanoyl-L-Homoserine lactone, N-3-hydroxybutyryl-L-HSL, N-3-hydroxybutanoyl-L-HSL)

カタログ番号GC46181

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N-3-hydroxybutyryl-L-Homoserine lactone 化学構造

Cas No.: 1325550-06-8

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1mg
$49.00
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5mg
$137.00
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10mg
$248.00
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Sample solution is provided at 25 µL, 10mM.

Description of N-3-hydroxybutyryl-L-Homoserine lactone

N-3-hydroxybutyryl-L-Homoserine lactone is an N-acyl-homoserine lactone produced by the bacterium V. splendidus and has been found in sequencing batch biofilm reactors used in wastewater treatment.1,2 It is the racemic version of the V. harveyi autoinducer N-((R)-3-hydroxybutanoyl)-L-homoserine lactone.3

|1. Purohit, A.A., Johansen, J.A., Hansen, H., et al. Presence of acyl-homoserine lactones in 57 members of the Vibrionaceae family. J. Appl. Microbiol. 115(3), 835-847 (2013).|2. Feng, Z., Sun, Y., Li, T., et al. Operational pattern affects nitritation, microbial community and quorum sensing in nitrifying wastewater treatment systems. Sci. Total Environ. 677, 456-465 (2019).|3. Ke, X., Miller, L.C., and Bassler, B.L. Determinants governing ligand specificity of the Vibrio harveyi LuxN quorum-sensing receptor. Mol. Microbiol. 95(1), 127-142 (2015).

Chemical Properties of N-3-hydroxybutyryl-L-Homoserine lactone

Cas No. 1325550-06-8 SDF
同義語 3-OH-C4-HSL, N-3-hydroxybutanoyl-L-Homoserine lactone, N-3-hydroxybutyryl-L-HSL, N-3-hydroxybutanoyl-L-HSL
Canonical SMILES OC(C)CC(N[C@@H]1C(OCC1)=O)=O
Formula C8H13NO4 M.Wt 187.2
溶解度 DMF: soluble; DMSO: soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of N-3-hydroxybutyryl-L-Homoserine lactone

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 5.3419 mL 26.7094 mL 53.4188 mL
5 mM 1.0684 mL 5.3419 mL 10.6838 mL
10 mM 0.5342 mL 2.6709 mL 5.3419 mL
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In vivo Formulation Calculator (Clear solution) of N-3-hydroxybutyryl-L-Homoserine lactone

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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