N-Acetyl-Ser-Asp-Lys-Pro acetate (Synonyms: Ac-SDKP acetate) |
| カタログ番号GC63718 |
N-Acetyl-Ser-Asp-Lys-Pro (Ac-SDKP) アセテートは、アンギオテンシン変換酵素 (ACE) の N 末端活性部位の特異的基質です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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N-Acetyl-Ser-Asp-Lys-Pro (Ac-SDKP) acetate is a specific substrate for the N-terminal active site of angiotensin-converting enzyme (ACE). N-Acetyl-Ser-Asp-Lys-Pro acetate is a natural inhibitor of pluripotent hematopoietic stem cell proliferation. Anti-inflammatory and antifibrotic properties[1][2].
[1]. Peng H, et al. Ac-SDKP reverses cardiac fibrosis in rats with renovascular hypertension. Hypertension. 2003;42(6):1164-1170.
[2]. Sharma U, et al. Novel anti-inflammatory mechanisms of N-Acetyl-Ser-Asp-Lys-Pro in hypertension-induced target organ damage. Am J Physiol Heart Circ Physiol. 2008;294(3):H1226-H1232.
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