N-methyl Paroxetine (Synonyms: Paroxetine-Related Compound F) |
| カタログ番号GC44419 |
N-メチルパロキセチンは、選択的セロトニン再取り込み阻害剤（SSRI）抗うつ薬であるパロキセチンの誘導体であり、[3H]パロキセチンがラットの大脳皮質膜に結合するのを阻害します（Ki = 4.3 nM）。
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Cas No.: 110429-36-2
Sample solution is provided at 25 µL, 10mM.
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N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine that inhibits [3H]paroxetine binding to rat cortical membranes (Ki = 4.3 nM). It inhibits serotonin uptake in rat brain synaptosomes with an IC50 value of 22 nM. N-methyl Paroxetine has been used as a precursor in the synthesis of paroxetine and is a potential impurity in commercial preparations of paroxetine.
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