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NBC 6

カタログ番号GC50611

NBC 6 は、Ca2+ とは独立して作用する強力な選択的 NLRP3 インフラマソーム阻害剤 (IC50 = 574 nM) です。

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NBC 6 化学構造

Cas No.: 2068818-02-8

サイズ 価格 在庫数 個数
10 mg
$288.00
在庫あり
50 mg
$1,199.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

NLRP3 inflammasome inhibitor (IC50 = 574 nM). Inhibits nigericin-induced inflammasome activation in THP-1 cells and Imiquimod induced IL-1β release from LPS-primed bone marrow-derived macrophages (BMDMs).

Baldwin et al (2017) Boron-based inhibitors of the NLRP3 inflammasome. Cell Chem.Biol. 24 1321 PMID:28943355

レビュー

Review for NBC 6

Average Rating: 5 ★★★★★ (Based on Reviews and 4 reference(s) in Google Scholar.)

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