Negletein |
| カタログ番号GC39070 |
ネグレテインは神経保護剤であり、神経成長因子の作用を高め、PC12 細胞の神経突起伸長を誘導します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 29550-13-8
Sample solution is provided at 25 µL, 10mM.
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Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 and 10.8 μM, respectively[1].
[1]. Phan CW, et al. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Biofactors. 2016 Nov 12;42(6):591-599. [2]. Singh B, et al. Anti-inflammatory and immunomodulatory flavones from Actinocarya tibetica Benth.Nat Prod Res. 2013;27(23):2227-30.
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