Nifekalant (hydrochloride) (Synonyms: MS-551) |
| カタログ番号GC44403 |
ニフェカラント (塩酸塩) (MS-551) は、クラス III の抗不整脈薬であり、IC50 が 10 μM の IKr カリウム チャネル遮断薬です。
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Cas No.: 130656-51-8
Sample solution is provided at 25 µL, 10mM.
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Nifekalant is a class III antiarrhythmic agent that has been shown to be beneficial to initial resuscitation after cardiac arrest in clinical trials. It blocks the rapidly activating delayed rectifier potassium channel (IKr; IC50 = 10 µM). Nifekalant is also inhibits the human multidrug and toxin extrusion (MATE) transporter 1 (MATE1; IC50 = 6.5 µM).
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
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