NO-1886 (Synonyms: Ibrolipim, Lipoprotein Lipase Activator, LPL Activator, OPF 009) |
| カタログ番号GC44432 |
NO-1886 (NO-1886) は、経口活性リポタンパク質リパーゼ (LPL) 促進剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 133208-93-2
Sample solution is provided at 25 µL, 10mM.
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Lipoprotein lipase (LPL) mediates the hydrolysis of triglycerides in circulating very low density lipoproteins and chylomicrons. NO-1886 is an LPL activator that increases LPL mRNA and LPL activity in adipose tissue, myocardium, and skeletal muscle. This coincides with an elevation in post-heparin plasma LPL activity and LPL mass in rats. NO-1886 decreases plasma triglyceride concentration and increases plasma high-density lipoprotein cholesterol, resulting in inhibited development of atherosclerotic lesions in coronary arteries and aortas of rats and rabbits.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
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