NOD2 antagonist 1 |
| カタログ番号GC65995 |
NOD2 アンタゴニスト 1 (化合物 32) は、IC50 が 5.23 μ の強力で選択的な NOD2 アンタゴニストです。 NOD2 アンタゴニスト 1 は、THP-1 細胞におけるムラミルジペプチド (MDP) 誘導性の IL-8 分泌を阻害し、MDP 誘導性の IL-6、IL-10、TNF-α を阻害します。 PBMC でのリリース。
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Cas No.: 2411441-54-6
Sample solution is provided at 25 µL, 10mM.
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NOD2 antagonist 1 (compound 32) is a potent and selective NOD2 antagonist with an IC50 of 5.23 μM. NOD2 antagonist 1 inhibits Muramyl dipeptide (MDP)-induced IL-8 secretion in THP-1 cells and inhibits MDP-induced IL-6, IL-10, TNF-α release in PBMCs[1].
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