Oseltamivir acid-d3 (Synonyms: GS 4071-d3; Ro 64-0802-d3; Oseltamivir carboxylate-d3) |
| カタログ番号GC63326 |
オセルタミビル酸 D3 (GS 4071 D3) は、重水素標識オセルタミビル酸です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1242184-43-5
Sample solution is provided at 25 µL, 10mM.
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Oseltamivir acid D3 (GS 4071 D3) is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].
[1]. Li W, et al. Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS 4071. Antimicrob Agents Chemother. 1998 Mar;42(3):647-53.
[2]. Ghosh GC, et al. Oseltamivir carboxylate, the active metabolite of oseltamivir phosphate (Tamiflu), detected in sewage discharge and river water in Japan. Environ Health Perspect. 2010 Jan;118(1):103-7.
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