P-CAB agent 2 hydrochloride |
| カタログ番号GC71224 |
P-CAB agent 2 hydrochlorideは、強力で経口活性のカリウム競合酸ブロッカーであり、胃酸分泌阻害剤である。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2209911-80-6
Sample solution is provided at 25 µL, 10mM.
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P-CAB agent 2 hydrochloride (100 µM) inhibits the hERG potassium channel with an inhibition rate of 86.21% and an IC50 value of 18.69 M[1].
P-CAB agent 2 hydrochloride (example 1) inhibits histamine -induced gastric acid secretion in SD rats[1].
P-CAB agent 2 hydrochloride (600, 2000 mg/kg; p.o.; once) shows no acute toxicity and 600mg/kg shows no significant effect on animal body weight in SD rats[1].
References:
[1]. YinLin Qin, et al. Pyrrole sulfonyl derivative, and preparation method and medical use thereof. WO2016119505A1.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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