Palmatine |
| カタログ番号GC39127 |
パルマチンは、HEK 293-hIDO-1 および rhIDO-1 に対してそれぞれ 3 μM および 157 μM の IC50 を持つ、経口活性で不可逆的なインドールアミン 2,3-ジオキシゲナーゼ 1 (IDO-1) 阻害剤です。
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Cas No.: 3486-67-7
Sample solution is provided at 25 µL, 10mM.
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Palmatine is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor. Palmatine can ameliorate DSS-induced colitis by mitigating colonic injury, preventing gut microbiota dysbiosis, and regulating tryptophan catabolism. Palmatine has the potential for colitis treatment[1].
[1]. Zhang XJ, et al. Palmatine ameliorated murine colitis by suppressing tryptophan metabolism and regulating gut microbiota.Pharmacol Res. 2018 Nov;137:34-46.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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