PD-1/PD-L1 inhibitor 2 (Synonyms: BMS202) |
| カタログ番号GC16762 |
PD-1/PD-L1 阻害剤 2 は、IC50 が 18 nM、KD が 8 μM の強力な非ペプチド性 PD-1/PD-L1 複合体阻害剤です。 PD-1/PD-L1 インヒビター 2 は PD-L1 に結合し、ヒト PD-1/PD-L1 相互作用をブロックします。 PD-1/PD-L1 阻害剤 2 には抗腫瘍活性があります。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1675203-84-5
Sample solution is provided at 25 µL, 10mM.
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BMS-202 is a potent PD-1/PD-L1 inhibitor, which binds to PD-1 and inhibits human PD-1/PD-L1 interaction, with an IC50 of 18 nM[1].
References:
[1]. Zak KM, et al. Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1). Oncotarget. 2016 May 24;7(21):30323-35.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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