PhosTAC7 |
| カタログ番号GC64344 |
三元複合体を誘導する PROTAC と同様に、PhosTAC7 はリン酸化基質に Ser/Thr ホスファターゼを動員してその脱リン酸化を仲介することに焦点を当てています。
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Cas No.: 3016307-75-5
Sample solution is provided at 25 µL, 10mM.
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Similar to PROTACs in their ability to induce ternary complexes, PhosTAC7 focuses on recruiting a Ser/Thr phosphatase to a phosphosubstrate to mediate its dephosphorylation.
[1]. Chen PH, et al. Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs). ACS Chem. Biol. 2021 Nov 15.
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