Phytosphingosine (Synonyms: D-ribo Phytosphingosine) |
| カタログ番号GC44640 |
フィトスフィンゴシンはリン脂質であり、抗がん作用があります。フィトスフィンゴシンは、がん細胞においてカスパーゼ 8 の活性化と Bax 転座を介して細胞アポトーシスを誘導します。
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Cas No.: 554-62-1
Sample solution is provided at 25 µL, 10mM.
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Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans. It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid as an intermediate. Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors. It is essential in the heat stress response in S. cerevisiae.
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