PKR-IN-C51 |
| カタログ番号GC64483 |
ＰＫＲ－ＩＮ－Ｃ５１（化合物５１）は、ＩＣ５０が９μＭのＡＴＰ競合二本鎖ＲＮＡ活性化プロテインキナーゼ（ＰＫＲ）阻害剤である。
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Cas No.: 1314594-23-4
Sample solution is provided at 25 µL, 10mM.
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PKR-IN-C51(compound 51) is an ATP-competitive double-stranded RNA-activated protein kinase (PKR) inhibitor with an IC50 of 9 μM. PKR-IN-C51 inhibits intracellular PKR activation in a dose-dependent manner in primary mouse macrophages[1].
[1]. Ruslana Bryk, et al. Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4108-14.
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