Polyvinylpyrrolidone (PVP K30) |
| カタログ番号GC32133 |
ポリビニルピロリドン (PVP) は、ヨウ素や他の化合物と組み合わせると、効果的な創傷治癒促進剤および消毒剤として、人間および獣医学で広くテストされ、使用されている化合物です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 9003-39-8
Sample solution is provided at 25 µL, 10mM.
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Polyvinylpyrrolidone is a compound that has been widely tested and used in human and veterinary medicine as an effective wound-healing accelerator and disinfectant when combined with iodine and other compounds.
Goldfishes that are treated with salt have significantly lower mucus weights at 25 h. Goldfishes treated with Polyvinylpyrrolidone (PVP) have significantly higher mucus weights at 25 h. Koi treated with salt and Polyvinylpyrrolidone (PVP) has significantly lower mucus weight at 1 and 25 h. Control koi has significantly higher mucus at 25 h. At the end of 2 weeks, it was determined that the three koi treated with salt and Polyvinylpyrrolidone(PVP) remained healthy and showed a higher degree of healing than other treatment koi and the control group[1].
References:
[1]. Shivappa RB, et al. Laboratory evaluation of different formulations of Stress Coat for slime production in goldfish (Carassius auratus) and koi (Cyprinus carpio). PeerJ. 2017 Sep 6;5:e3759.
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Animal experiment: |
Each fish within a tank serves as a replicate. Treatments are designated as Polyvinylpyrrolidone (at a dose of 10 mL/10 gallon) and saline/salt at 3g/L. A control group that does not receive any chemical is also included in the study. All fishes from each treatment group are sampled at 0 min, 15 min, 1 h, 4 h and 25 h. At each time interval, all fishes from each treatment group are anaesthetized using buffered tricaine methanesulfonate, weighed, and slime is scraped from one 1 cm2 area over the epaxial musculature using a preweighed plastic coverslip[1]. |
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References: [1]. Shivappa RB, et al. Laboratory evaluation of different formulations of Stress Coat for slime production in goldfish (Carassius auratus) and koi (Cyprinus carpio). PeerJ. 2017 Sep 6;5:e3759. |
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| Cas No. | 9003-39-8 | SDF | |
| Canonical SMILES | O=C1CCCN1C(C[H])[H].[n] | ||
| Formula | (C6H9NO)n | M.Wt | ~40,000 |
| 溶解度 | DMSO : 50 mg/mL ;Water : ≥ 50 mg/mL | Storage | Store at RT |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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