Pomalidomide 4'-alkylC6-amine (hydrochloride) |
カタログ番号GC91584 |
Pomalidomide 4'-alkylC6-amine is a building block in the synthesis of proteolysis-targeting chimeras (PROTACs) and a derivative of the cereblon inhibitor pomalidomide .
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Cas No.: 2375194-37-7
Sample solution is provided at 25 µL, 10mM.
Pomalidomide 4'-alkylC6-amine is a building block in the synthesis of proteolysis-targeting chimeras (PROTACs) and a derivative of the cereblon inhibitor pomalidomide .[1] It has been used in the synthesis of PROTACs containing BRD73954 that drive histone deacetylase 8 (HDAC8) degradation.
References:
[1].Sun, Z., Deng, B., Yang, Z., et al.Discovery of pomalidomide-based PROTACs for selective degradation of histone deacetylase 8Eur. J. Med. Chem.239114544(2022).
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