Pravastatin-d3 (sodium salt) |
| カタログ番号GC40220 |
プラバスタチン-d3 (CS-514-d3) ナトリウム塩は、重水素標識プラバスタチン ナトリウム塩です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1329836-90-9
Sample solution is provided at 25 µL, 10mM.
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Pravastatin-d3 is intended for use as an internal standard for the quantification of pravastatin by GC- or LC-MS. Pravastatin is a potent and competitive HMG-CoA reductase inhibitor (Ki = 2.3 nM for the active, open ring form of the molecule) that is a ring-hydroxylated metabolite of mevastatin . In vivo, pravastatin reduces total plasma cholesterol levels by 29% in dogs when administered at a dose of 20 mg/kg per day for five weeks. Formulations containing pravastatin have been used to reduce LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease.
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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