Prochlorperazine dimaleate |
| カタログ番号GC50039 |
D2受容体拮抗剤；また、5-HT3およびnAChR拮抗剤
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1984/2/6
Sample solution is provided at 25 µL, 10mM.
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D2 receptor antagonist. Also interacts with 5-HT3 and nAChR. Displays antipsychotic, antispasmodic, antiemetic and antinociceptive activity in vivo.
Lummis and Baker (1997) Radioligand binding and photoaffinity labeling studies show a direct interaction of phenothiazenes at 5-HT3 receptors. Neuropharmacology 36 665 PMID:9225292 |Ghelardini et al (2004) Prochlorperazine induces central antinociception mediated by the muscarinic system. Pharmacol.Res. 50 351 PMID:15225680 |Satoh et al (2005) The antipsychotic and antiemetic drug prochlorper. delays the ventricular repolarization of the in situ canine heart. J.Pharm.Sci. 97 101
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