Propargyl-PEG7-Boc |
カタログ番号GC67132 |
プロパルギル-PEG7-Boc は、PROTAC の合成に使用できる PEG ベースの PROTAC リンカーです。
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Cas No.: 1818294-29-9
Sample solution is provided at 25 µL, 10mM.
Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2.
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