Prostaglandin D2 methyl ester (Synonyms: PGD2 methyl ester) |
カタログ番号GC41170 |
プロスタグランジンD2(PGD2)は、マスト細胞の主要なエイコサノイド産物であり、アレルギー性および喘息性アナフィラキシー中に造血性PGD合成酵素によって大量に生成されます。
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Cas No.: 49852-81-5
Sample solution is provided at 25 µL, 10mM.
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. It causes vasodilation, flushing, hypotension, and is an inhibitor of platelet aggregation. Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2. It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.
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