Prostaglandin D2 serinol amide (Synonyms: PGD2SA) |
| カタログ番号GC44709 |
2-アラキドニルグリセロール（2-AG）は、CB1受容体でカンナビノイド（CB）アゴニスト活性を示し、重要な内因性単グリセリド種であり、したがってCB1受容体の自然なリガンドと考えられています。
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Cas No.: 851761-42-7
Sample solution is provided at 25 µL, 10mM.
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2-Arachidonyl glycerol (2-AG) exhibits cannabinoid (CB) agonist activity at the CB1 receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor. 2-AG can also be sequentially metabolized by COX-2 and specific PG synthases to form PG 2-glyceryl esters. In activated RAW 264.7 cells, PGD2 2-glyceryl ester is the primary product of 2-AG metabolism in the COX pathway. PGD2 serinol amide (PGD2-SA) is a stable analog of PGD2 2-glyceryl ester. Unlike PGD2 2-glyceryl ester and other fatty acyl 2-glyceryl esters, PGD2-SA will not isomerize to the less active primary (1-glyceryl) ester. The biological activity of PGD2-SA has not yet been determined.
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