PROTAC TYK2 degradation agent1 |
| カタログ番号GC71201 |
PROTAC TYK2 degradation agent1 は、強力でサブタイプ選択的なtyk2分解器です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2921556-14-9
Sample solution is provided at 25 µL, 10mM.
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PROTAC TYK2 degradation agent1 (degrader 37) (1 µM; 6 h) selectively suppresses TYK2 protein levels[1].
PROTAC TYK2 degradation agent1 has TYK2 degradation activity with DC50 value of 14 nM[1].
References:
[1]. Jun-Ya Kato, et al. Discovery of a potent and subtype-selective TYK2 degrader based on an allosteric TYK2 inhibitor. Bioorg Med Chem Lett. 2023 Jan 1;79:129083.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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