Prunetrin (Synonyms: Trifoside; Prunetin 4′-O-β-D-glucopyranoside) |
| カタログ番号GC61218 |
プルネトリン (Trifoside) は、レッド クローバーの地上および地下器官に見られるソフラボノイドです 。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 154-36-9
Sample solution is provided at 25 µL, 10mM.
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Prunetin (Trifoside), an O-methylated isoflavone found in Prunus yedoensis, possesses anti-inflammatory activities[1][2].
Prunetin inhibits LPS-induced nitric oxide and prostaglandin E2 production through the suppression of iNOS and COX-2 at the transcriptional level[1].Prunetin inhibits lipopolysaccharide-induced inflammatory cytokine production and MUC5AC expression by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells[2].
[1]. Yang G, et al. Anti-inflammatory effect of prunetin via the suppression of NF-κB pathway. Food Chem Toxicol. 2013;58:124-132. [2]. Hu H, et al. Prunetin inhibits lipopolysaccharide-induced inflammatory cytokine production and MUC5AC expression by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells. Biomed Pharmacother. 2018;106:1469-1477.
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