Purine riboside-5'-O-triphosphate (sodium salt) |
| カタログ番号GC90883 |
ネブラリンの活性代謝物
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 35892-95-6
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Purine riboside-5'-O-triphosphate (PRTP) is an active metabolite of the antiviral, antibacterial, and anticancer agent nebularine .1 It is formed from nebularine by adenosine kinase, which results in depletion of intracellular ATP levels and induces cell death in isolated rat tmocytes, an effect that can be reduced by the adenosine kinase inhibitor 5-iodotubercidin . PRTP is an inhibitor of DNA primase ATP and GTP polymerization activities (IC50s = 35 and 28 µM, respectively, for the human enzyme) and of calmodulin-dependent protein kinase II (CaMKII; Ki = 590 µM).2,3
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *