Py-BODIPY-NHS ester |
カタログ番号GC60313 |
Py-BODIPY-NHS エステルは、細胞透過性の蛍光エネルギー移動プローブです。 Py-BODIPY-NHS エステル トレーサーは強力な細胞関与をもたらし、MET キナーゼに最適であることが証明されています。生細胞のエネルギー移動技術は、細胞内キナーゼ ターゲット エンゲージメントの広範囲の定量分析を実行できます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 201998-61-0
Sample solution is provided at 25 µL, 10mM.
Py-BODIPY-NHS ester is a cell-permeable and fluorescent energy transfer probe. Py-BODIPY-NHS ester tracer yields strong cellular engagement and proves to be optimal for MET kinase. The live-cell energy transfer technique can perform a broad-coverage, quantitative analysis of intracellular kinase target engagement[1][2].
Triphenylphosphonium-fluorochromes (TPP-fluorochromes) are a new class of spectrally variable, mitochondrially targeted probes. NanoBRET 590 SE (compound 2b) is synthesized by reacting the TPP-amine with NHS esters of BODIPY red[3].
[1]. Vasta JD, et al. Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of CellularATP on Target Engagement. Cell Chem Biol. 2018 Feb 15;25(2):206-214.e11. [2]. Robers MB, et al. Quantitative, Real-Time Measurements of Intracellular Target Engagement Using Energy Transfer. Methods Mol Biol. 2019;1888:45-71. [3]. Yuan H, et al. Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria. Chem Commun (Camb). 2013 Nov 14;49(88):10361-3.
Average Rating: 5
(Based on Reviews and 23 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *