(Pyr3)-Amyloid β-Protein (3-42) (TFA) |
| カタログ番号GC72239 |
(Pyr3)-Amyloid β-Protein (3-42) (TFA)はアルツハイマー病とダウン症候群患者の脳に堆積した主要なアミロイドβペプチド構造である。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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(Pyr3)-Amyloid β-Protein (3-42) TFA is the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. (Pyr3)-Amyloid β-Protein (3-42) TFA is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits.
References:
[1]. Takahashi-Ito K, et.al. Memantine inhibits β-amyloid aggregation and disassembles preformed β-amyloid aggregates. Biochem Biophys Res Commun. 2017 Nov 4;493(1):158-163.
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