Pyridomycin (Synonyms: Erizomycin, NSC 246134) |
| カタログ番号GC40825 |
ピリドマイシンは、構造的に異常な抗酸菌サイクロデプシペプチドであり、その組成には3-(3-ピリジル)-L-アラニンと2-ヒドロキシ-3-メチルペント-2-エノ酸の2つの珍しい部分が含まれています。
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Cas No.: 18791-21-4
Sample solution is provided at 25 µL, 10mM.
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Pyridomycin is a structurally unusual antimycobacterial cyclodepsipeptide whose composition includes two rare moieties: 3-(3-pyridyl)-L-alanine and 2-hydroxy-3-methylpent-2-enoic acid. It inhibits NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis, including isoniazid-resistant strains (MICs = 0.31-0.63 µg/ml).
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
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