QPX7728-OH disodium (Synonyms: QPX7728 disodium) |
| カタログ番号GC62237 |
ゼルボルバクタム (QPX7728) 二ナトリウムは、強力な超広域スペクトルのボロン酸ベータ-ラクタマーゼ阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2170848-99-2
Sample solution is provided at 25 µL, 10mM.
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QPX7728-OH disodium (compound 13) is a boronic acid β-lactamase inhibitor, exacted from WO2018005662A1, compound 13. QPX7728-OH disodium inhibits cleavage of Nitrocefin by purified class A, C and D enzymes, with Kis less than 0.1 µμ[1].
QPX7728-OH disodium potentiates Aztreonam and Tigemonam against strains expressing class A and class C enzymes, with MICs≤5 µg/mL. QPX7728-OH disodium potentiates Biapenem against strains expressing class A (KPC) or class D (OXA-48) carbapenemases, with MICs≤5 µg/mL[1].
[1]. Scott Hecker, et al. Boronic acid derivatives and therapeutic uses thereof. WO2018005662A1.
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