(R)-eIF4A3-IN-2 |
| カタログ番号GC62738 |
(R)-eIF4A3-IN-2 は、eIF4A3-IN-2 の活性の低いエナンチオマーです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2095484-82-3
Sample solution is provided at 25 µL, 10mM.
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(R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM[1].
Eukaryotic initiation factor 4A-3 (eIF4A3) is an Asp-Glu-Ala-Asp (DEAD) box-family adenosine triphosphate (ATP)-dependent RNA helicase[1].
[1]. Iwatani-Yoshihara M, et al. Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay. ACS Chem Biol. 2017;12(7):1760-1768.
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
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