(Rac)-Finerenone (Synonyms: (Rac)-BAY 94-8862) |
| カタログ番号GC62332 |
(Rac)-Finerenone ((Rac)-BAY 94-8862) は、Finerenone のラセミ体です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1050477-27-4
Sample solution is provided at 25 µL, 10mM.
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(Rac)-Finerenone ((Rac)-BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold)[1].
[1]. BÄrfacker L, et al. Discovery of BAY 94-8862: a nonsteroidal antagonist of the mineralocorticoid receptor for the treatment of cardiorenal diseases. ChemMedChem. 2012;7(8):1385-1403.
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