Raddeanin A |
| カタログ番号GC19607 |
ラデアニン A は、アネモネ ラデアナの天然のトリテルペノイド サポニン成分であり、抗がん作用があります。ラデアニン A は、ROS/JNK および NF-κB シグナル経路を介してヒト骨肉腫に抗がん効果を発揮します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 89412-79-3
Sample solution is provided at 25 µL, 10mM.
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Raddeanin A is a natural triterpenoid saponin component of Anemone raddeana, with anti-cancer activities. Raddeanin A exerts anticancer effect on human osteosarcoma via the ROS/JNK and NF-κB signal pathway[1][2][3][4].
[1]. Ma B, et al. Raddeanin A, a natural triterpenoid saponin compound, exerts anticancer effect on human osteosarcoma via the ROS/JNK and NF-κB signal pathway. Toxicol Appl Pharmacol. 2018 Aug 15;353:87-101. [2]. Guo SS, et al. Raddeanin A promotes apoptosis and ameliorates 5-fluorouracil resistance in cholangiocarcinoma cells. 3.411World J Gastroenterol. 2019 Jul 14;25(26):3380-3391. [3]. Xia H, et al. Raddeanin A down-regulates androgen receptor and its splice variants in prostate cancer. J Cell Mol Med. 2019 May;23(5):3656-3664. [4]. Meng C, et al. Raddeanin A Induces Apoptosis and Cycle Arrest in Human HCT116 Cells through PI3K/AKT Pathway Regulation In Vitro and In Vivo. Evid Based Complement Alternat Med. 2019 May 26;2019:7457105.
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