1,4-Chrysenequinone (Chrysene-1,4-dione) |
カタログ番号GC33314 |
1,4-クリセンキノン (クリセン-1,4-ジオン) は、多環式芳香族キノンであり、アリール炭化水素受容体 (AhR) の活性化剤として機能します。
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Cas No.: 100900-16-1
Sample solution is provided at 25 µL, 10mM.
1,4-Chrysenequinone (Chrysene-1,4-dione), a polycyclic aromatic quinone, acts as an activator of aryl hydrocarbon receptor (AhR).
1,4-Chrysenequinone shows significant AhR ligand activity, with ECTCDD25s (concentration equivalent with 25% of TCDD max) of 9.7 nM and 1.9 μM in yeast and mouse hepatoma cell systems, respectively[1].
[1]. Misaki K, et al. Aryl hydrocarbon receptor ligand activity of polycyclic aromatic ketones and polycyclic aromatic quinones. Environ Toxicol Chem. 2007 Jul;26(7):1370-9.
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