5-Hydroxylansoprazole |
| カタログ番号GC60530 |
5-ヒドロキシランソプラゾール (AG1908) は、血漿中のランソプラゾールの活性代謝物です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 131926-98-2
Sample solution is provided at 25 µL, 10mM.
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5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole in plasma. Lansoprazole is metabolized by CYP2C19 forming 5-Hydroxylansoprazole. Lansoprazole is a gastric proton-pump inhibitor and is effective in the treatment of various peptic diseases[1][2].
[1]. Xu HR, et al. The effect of CYP2C19 activity on pharmacokinetics of lansoprazole and its active metabolites in healthy subjects. Pharm Biol. 2010 Aug;48(8):947-52. doi: 10.3109/13880200903300220. [2]. KatarÍna KostolanskÁ, et al. Determination of lansoprazole, 5-hydroxylansoprazole, and lansoprazole sulfone in human plasma for CYP2C19 and CYP3A4 phenotyping. Chemical Papers. volume 73, pages2955-2963(2019).
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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