8,12-iso-iPF2α-VI (Synonyms: 8,12-iso-Isoprostane-F2α-VI, 12-iso-5,6E,14Z-PGF2α, 12iso5,6E,14ZProstaglandin F2α) |
カタログ番号GC40587 |
8,12-iso-iPF2α-VIは、膜リン脂質の非酵素的なフリーラジカル誘導性過酸化ダメージによって生成されるイソプロスタンです。
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Cas No.: 1445349-99-4
Sample solution is provided at 25 µL, 10mM.
8,12-iso-iPF2α-VI is an isoprostane produced by non-enzymatic, free radical-induced peroxidative damage to membrane lipids. It is the most abundant isoprostane product that is formed during lipid peroxidation and is used as a biomarker for oxidative stress. 8,12-iso-iPF2α-VI is detected after CCl4-induced oxidative damage to hepatic tissue and has been found elevated in the urine, blood, and cerebrospinal fluid of patients with Alzheimer's disease.
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