β-Apooxytetracycline (Synonyms: β-Apo-Oxytetracycline, β-Apoterramycin) |
カタログ番号GC45225 |
β-アポオキシテトラサイクリンは、オキシテトラサイクリンの商業的な製剤に見つかる潜在的な不純物です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 18751-99-0
Sample solution is provided at 25 µL, 10mM.
β-Apooxytetracycline is a potential impurity found in commercial preparations of oxytetracycline. β-Apooxytetracycline is a degradation product formed from oxytetracycline via acid hydrolysis. It has a relative potency of 0.1 compared with oxytetracycline for inhibiting the growth of aerobic sludge bacteria, an MIC50 value of 32 mg/L for tetracycline-sensitive strains of Pseudomonas, and MIC50 values of greater than 32 mg/L for tetracycline-sensitive strains of Agrobacterium, Moraxella, and Bacillus, as well as tetracycline-resistant strains of E. coli. β-Apooxytetracycline (10 mg/kg) is toxic to rats, decreasing body weight, disrupting blood cell counts, and inducing hepatocyte necrosis.
Average Rating: 5
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