BigLEN (mouse) |
| カタログ番号GC50414 |
BigLEN (マウス) は、オーファン G タンパク質共役受容体 171 (GPR171) の強力かつ選択的なアゴニストであり、Kd は約 0.5 nM です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 501036-69-7
Sample solution is provided at 25 µL, 10mM.
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GPR171 agonist. ProSAAS-derived neuropeptide. Regulates food intake in mice. Inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins.
Wardman et al (2011) ProSAAS-derived peptides are colocalized with neuropeptide Y and function as neuropeptides in the regulation of food intake. PLoS One 6 e28152 PMID:22164236 |Mack et al (2019) Neuropeptide PEN and its receptor GPR83: distribution, signaling, and regulation. ACS Chem.Neurosci. 10 1884 PMID:30726666
Average Rating: 5 (Based on Reviews and 16 reference(s) in Google Scholar.)
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